话不多说，报错如下：

  × Getting requirements to build wheel did not run successfully.
  │ exit code: 1
  ╰─> [24 lines of output]
      Trying pkg-config --exists mysqlclient
      Command 'pkg-config --exists mysqlclient' returned non-zero exit status 1.
      Trying pkg-config --exists mariadb
      Command 'pkg-config --exists mariadb' returned non-zero exit status 1.
      Trying pkg-config --exists libmariadb
      Command 'pkg-config --exists libmariadb' returned non-zero exit status 1.
      Traceback (most recent call last):
        File "/root/anaconda3/envs/zhaopin/lib/python3.10/site-packages/pip/_vendor/pyproject_hooks/_in_process/_in_process.py", line 353, in 
          main()
        File "/root/anaconda3/envs/zhaopin/lib/python3.10/site-packages/pip/_vendor/pyproject_hooks/_in_process/_in_process.py", line 335, in main
          json_out['return_val'] = hook(**hook_input['kwargs'])
        File "/root/anaconda3/envs/zhaopin/lib/python3.10/site-packages/pip/_vendor/pyproject_hooks/_in_process/_in_process.py", line 118, in get_requires_for_build_wheel
          return hook(config_settings)
        File "/tmp/pip-build-env-o5wmabdl/overlay/lib/python3.10/site-packages/setuptools/build_meta.py", line 325, in get_requires_for_build_wheel
          return self._get_build_requires(config_settings, requirements=['wheel'])
        File "/tmp/pip-build-env-o5wmabdl/overlay/lib/python3.10/site-packages/setuptools/build_meta.py", line 295, in _get_build_requires
          self.run_setup()
        File "/tmp/pip-build-env-o5wmabdl/overlay/lib/python3.10/site-packages/setuptools/build_meta.py", line 311, in run_setup
          exec(code, locals())
        File "", line 155, in 
        File "", line 49, in get_config_posix
        File "", line 28, in find_package_name
      Exception: Can not find valid pkg-config name.
      Specify MYSQLCLIENT_CFLAGS and MYSQLCLIENT_LDFLAGS env vars manually
      [end of output]
  
  note: This error originates from a subprocess, and is likely not a problem with pip.
error: subprocess-exited-with-error

关键问题就在这一句：

Exception: Can not find valid pkg-config name.
Specify MYSQLCLIENT_CFLAGS and MYSQLCLIENT_LDFLAGS env vars manually

异常:找不到有效的pkg-config名称。 手动指定MYSQLCLIENT_CFLAGS和MYSQLCLIENT_LDFLAGS环境变量

 官网上其实给出了解答：

 # Debian / Ubuntu

sudo apt-get install python3-dev default-libmysqlclient-dev build-essential pkg-config 

# Red Hat / CentOS

sudo yum install python3-devel mysql-devel pkgconfig

 Mac 

macOS (Homebrew)

Install MySQL and mysqlclient（如果要安装MySQL）:

$ # Assume you are activating Python 3 venv
$ brew install mysql pkg-config
$ pip install mysqlclient

If you don't want to install MySQL server, you can use mysql-client instead(不要安装MySQL):

$ # Assume you are activating Python 3 venv
$ brew install mysql-client pkg-config
$ export PKG_CONFIG_PATH="$(brew --prefix)/opt/mysql-client/lib/pkgconfig"
$ pip install mysqlclient

官网文档：

  https://github.com/PyMySQL/mysqlclient#user-content-macos-homebrew